A Dietitian’s Honest Review: Flo Ovarian Support

Looking for a real Flo Ovarian Support review? As a registered dietitian, who specializes in PCOS and hormone health, I’ve got you covered. 

This blog post will dive into what’s in the Flo Ovarian Support vitamin capsules, what the research says, the pros and cons of this supplement, and if I think it’s actually worth it.

What Are Flo Ovarian Support Vitamins? 

Flo Ovarian Support Vitamin Capsules are a dietary supplement created by the US-based company O Positiv Health. It’s a blend of nutrients and claims that it supports healthy ovulation and hormone balance. The company recommends daily consumption of this supplement for at least 3 months to feel the full effects.

Flo Ovarian Support Health Claims

O Positiv Health claims that Flo Ovarian Support ingredients support:

• Healthy ovulation
• Reproductive health
• Cycle regularity
• Hormonal weight management

Ok, this seems promising, right? Let’s take a look at what’s actually in this supplement and what the research says.

Flo Ovarian Support Ingredients

Here’s what’s actually inside the Flo Ovarian Support Vitamin Capsules:

1. Folate (as folic acid) 680 mcg DFE

Folate is also known as vitamin B9. It’s naturally occurring in a wide variety of food sources such as spinach, black eyed peas, asparagus, Brussels sprouts, and rice. 

Folic acid is a synthetic form of folate. Because of its low cost, it’s frequently used in prenatal vitamins or added to certain foods such as fortified cereals. 

Folate and folic acid are important for pregnancy, particularly for preventing neural tube defects like spina bifida. More recently, research has linked folate to an improvement in fertility and reproductive health. 

In fact, recent studies have found that higher folate intake is associated with:

• Lower risk of anovulation and ovulatory infertility
• Shorter time to get pregnant
• Greater success with infertility treatment

The recommended dietary allowance (RDA) for folate for adult women is 400 mcg DFE. During pregnancy, the RDA increases to 600 mcg DFE, and 500 mcg DFE while breastfeeding. 

Flo Ovarian Support contains 680 mcg DFE as folic acid, which meets and exceeds the RDA for adult women, regardless of pregnancy status. However, since folate is a water soluble vitamin, higher amounts are generally not dangerous for the general population.

There is some debate as to whether the synthetic form folic acid is well absorbed by those with the common MTHFR gene variation (1). 

As with any supplement, it’s always a good idea to talk to your healthcare provider to ensure it’s a good choice for you. 

2. Myo-Inositol 2000 mg + D-chiro-inositol 50 mg

Inositol is the most well-studied supplement for PCOS (polycystic ovary syndrome) and other hormonal conditions. Honestly, it has some pretty impressive results too. The Flo Ovarian Support blend of myo-inositol and d-chiro inositol has the same 40:1 ratio that I typically recommend if you’re going to try inositol. 

Inositol can help: 

• Improve glucose levels and insulin sensitivity
• Decrease body weight and BMI
• Reduce inflammation  
• Lower high cholesterol levels
• Reduce carbohydrate cravings
• Lower testosterone levels, which can be contributing to hormonal acne, hirsutism (aka unwanted hair growth like facial hair and body hair) and hair loss
• Restore ovulation and promote regular menstrual cycles
• Increase fertility by improving egg quality, pregnancy rates, and IVF outcomes 
• Decrease the risk of gestational diabetes in pregnancy
• Improve thyroid function in hypothyroidism

Myo-inositol alone can have positive effects on hormone health. However, research seems to favor the myo-inositol plus d-chiro inositol blend, especially if weight loss is one of your goals (2).

The recommended dosage of inositol is 2,000 to 4,000 mg myo-inositol plus 50 to 100 mg d-chiro inositol daily, so the amount used in this supplement falls within the lower end of the recommended range. 

3. Diindolymethane (DIM) 100 mg

DIM is a compound that your body naturally makes when you eat cruciferous vegetables like kale, brussels sprouts, broccoli, and cauliflower. It’s also available in supplement form.

Despite limited research, DIM has gained popularity as a potential treatment option for acne, estrogen imbalances, certain cancers, and menopausal symptoms. 

DIM helps to support natural estrogen detoxification pathways. If you have irregular periods or PMS symptoms, your estrogen levels may be out of balance with your progesterone levels. This can lead to a variety of symptoms like irregular periods, painful periods, menstrual cramps, breast tenderness, and migraines.

Estrogen imbalances can also promote subcutaneous fat storage and lead to weight gain. So in theory, if DIM can support estrogen detoxification, it may be able to help promote regular periods, less PMS symptoms, and even weight loss.

DIM is available as supplements in two forms. One form is a generic crystalline formulation, which is not well absorbed by the body. Another form is a microencapsulated form called BioResponse-DIM (BR-DIM), which is much better absorbed and is the form that most research studies used (3). Most human studies have used dosages of anywhere between 100 to 300 mg DIM in supplement form.

Flo Ovarian Support contains 100 mg, which falls at the lower end of the range that may be beneficial according to human studies. I reached out to O Positiv by email and they confirmed that their Flo Ovarian Support supplement doesn’t use the BR-DIM form, which is absorbed significantly better.  

Flo Ovarian Support Side Effects + Safety

As with any dietary supplement, Flo Ovarian Support may cause some side effects for some people. 

The most common side effects include gastrointestinal issues, such as nausea, upset stomach, and diarrhea. Other side effects include hypoglycemia, fatigue, headaches, lightheadedness, and menstrual cycle disturbances. 

Most people experience mild side effects and they often will resolve as your body adjusts to this dietary supplement. 

It’s important to note that DIM, an ingredient in Flo Ovarian Support, is not safe for pregnancy or breastfeeding. 

Pros of Flo Ovarian Support

• Third Party Tested. The Food and Drug Administration (FDA) does not regulate or approve of any dietary supplements, their labeling, or health claims. It’s not unusual to find supplements on the market that don’t actually have what they’re advertising inside their supplements. OPositiv Health does claim their supplements, including the Flo Ovarian Support vitamin capsules, are third party tested for purity and quality. 

• 3 Capsules Dose. This may be a con for you, but, if you do truly need all of these nutrients, this could be an effective way to get them in a one-and-done 3 capsule serving.

• Good Inositol Ratio. The ratio of myo-inositol to d-chiro-inositol in this supplement is 40:1, which is the same ratio that’s naturally found in our bodies and the amount I typically recommend if you’re going to supplement with inositol.

• Vegan Capsules. The capsules are classified as vegan, making them suitable for those who follow a vegetarian diet or a vegan diet. 

Cons of Flo Ovarian Support

Alright, now that we’ve touched on the pros, there are some cons that you’ll want to consider. 

• 3 Capsules Dose. I know this was listed as a pro, but it could be a con if you struggle with swallowing pills. 

• Possibly Unnecessary. While the marketing is appealing and seemingly a solution if you struggle with anything in regards to abnormal periods, you may not need all of these nutrients in the dosages that are provided. Dietary supplements are often regarded as safe and natural, but too much or too little of certain nutrients can render them useless or even dangerous. Consider nutrient overlap too that can happen, especially if you’re taking a prenatal vitamin, multivitamin, or other supplements. 

• Potentially Inadequate Dosage. The nutrients found in Flo Ovarian Support, particularly the myo-inositol, d-chiro-inositol, and DIM are on the lower end of the recommended ranges. Depending on your unique needs, this may not be an adequate dose to actually see the results you’re looking for.

• Folate Form. This may not be a con for everyone, but the folate form used in this supplement is folic acid, the synthetic form of folate. Some research indicates that folic acid isn’t well absorbed and tolerated by everyone. 

• Cost.This is perhaps the biggest drawback in my opinion. The cost of this product seems high for what you’re getting. If all of these nutrients are appropriate for you, and the doses are the right amounts for you, you can easily find these products at a lower price point. I’ll outline some options in the sections below. 

Should You Take Flo Ovarian Support?

Maybe. Maybe not. There’s no magic bullet that will work for everyone. I’ve outlined the pros and cons of this dietary supplement above. If you need all of these nutrients, in the forms and doses provided, this can be a good option for you. It offers a convenient monthly shipment if you sign up for the subscription at a discounted price.

The ingredients in Flo Ovarian Support can help support hormonal balance, healthy hormone levels and ovulation, pregnancy goals, and symptoms of PCOS. 

That said though, the myoinositol, d-chiro inositol, and DIM dosage is at the lower end of the recommended ranges. The type of DIM used in this supplement isn’t as well absorbed as other types. And finally, folic acid may not be well utilized for some people.

DIM is also not safe for pregnancy and breastfeeding. If fertility is your goal, it may make more sense to take inositol and folate supplements separately since they can be safely continued during pregnancy. Additionally, prenatal vitamins typically have similar amounts of folate/folic acid in them as Flo vitamins does.  

If you do need all of these nutrients and the price is making you think twice about it, it’s easy to find the same nutrients in more cost effective ways if you order them separately: 

• Inositol: get it in a 2 month supply or a 6 month supply. Read about the 3 best inositol supplements on the market, including a capsule form if that’s your preference.
• Folic Acid (over 6 month supply)
• DIM (90 day supply)

If you won’t benefit from all of these nutrients, Flo Ovarian Support is an expensive and potentially unnecessary purchase. Always talk to your medical doctor or healthcare provider prior to starting any new supplements. 

FAQs

Does Flo Ovarian Support Help You Get Pregnant?

Depending on your unique circumstances and medical conditions, this may help you to achieve more regular periods, improve egg quality, and ultimately become pregnant. Of course, individual results will vary and you should always consult with your medical team prior to considering any new dietary supplements. 

If you have PCOS and are trying to achieve pregnancy, do not miss this post: How To Get Pregnant with PCOS Quickly + Naturally.

Does Flo Ovarian Support work for PCOS?

Inositol is the most well-studied supplement for PCOS. Flo Ovarian Support contains the ideal 40:1 ratio of myoinotisol and d-chiro inositol, albeit at the lower end of the recommended dosage range. 

Based on the fact that this supplement contains these types of inositol, it can help to improve PCOS symptoms. 

Read more about the benefits of inositol for PCOS and the best inositol brands for PCOS.

How Does Flo Ovarian Support Work?

The ingredients in Flo Ovarian Support include an inositol blend, folic acid, and DIM. These nutrients may help to lower blood sugar levels, insulin resistance, inflammation, estrogen, and testosterone levels. This can help to promote more regular periods and less PMS symptoms. 

Additionally, folic acid is the synthetic form of folate, a key nutrient for reproductive health and ovulation. It’s also a key nutrient in the prevention of neural tube defects in pregnancy. 

What Are The Side Effects of Myo-Inositol?

Myo-inositol is a compound that’s naturally found in foods such as cantaloupe, walnuts, and beans. Side effects are rare but may include hypoglycemia (aka low blood sugar) or digestive upset. 

The Bottom Line

Flo Ovarian Support is a dietary supplement that includes folate (as folic acid), myoinositol, d-chiro inositol, and DIM. There is research to support that these ingredients can support hormone balance, irregular periods, fertility, and PCOS symptoms.

Whether you need, or would benefit from, all three of these ingredients together is debatable. Many people could see results with just one supplement at a lower price point. 

Folic acid is a really affordable supplement that may not be well absorbed by everyone. Additionally, the DIM used in Flo is not well absorbed so it’s difficult to determine if it’s even worthwhile. It’s also not considered safe for pregnancy or breastfeeding so if fertility is your goal, this may not actually be the best supplement. The inositol dosages are therapeutic, however, they’re at the low end of the recommended range. 

If you need all three of the ingredients in Flo Ovarian Support, this may be a good option for you. If you do not, you may want to consider supplementing with individual ingredients instead. These are some alternatives that are equal (or better) than the ingredients in Flo Ovarian Support: 

• Inositol: get it in a 2 month supply or a 6 month supply. Read about the 3 best inositol supplements on the market, including a capsule form if that’s your preference.
• Folic Acid (over 6 month supply)
• DIM (90 day supply)

Always discuss new supplements with your medical provider. 

Other Supplement Reviews You’ll Love

A Dietitian’s Review of Happy Hormones PCOS Multivitamin 

Is S’moo For You? A PCOS Dietitian’s Honest Review

The 5 Best Prenatal Vitamins

8 Ovasitol Benefits for Hormones

Can I Take Berberine & Inositol Together?

Disclaimer: this is for informational purposes only. It is not intended to substitute for or replace professional medical advice. Always consult with your health care provider before starting or stopping any dietary supplements or medications.