A PCOS Dietitian’s Review of Wynk Soul Cyster

Have you been seeing ads for Soul Cyster supplements? These PCOS targeted supplements by Wynk seem to be everywhere I look. 

As a registered dietitian who also has PCOS, I’m going to give you a full Wynk Soul Cyster review. In this blog post, I’m breaking down what’s in these supplements and what the research says to help you decide if they’re a good fit for you.

This post may contain affiliate links. This means that if you click on a link and make a purchase, I may receive a small commission at no additional cost to you. 

What is Wynk Nu Soul Cyster? 

Soul Cyster is made by the US-based company Wynk. It was developed by two sisters with PCOS. 

Soul Cyster is a powder blend of essential nutrients that comes in individual serving packets. You mix one packet with water daily. The company recommends that you should take it for a minimum of two to three months to see the full effect.

Soul Cyster Health Claims

Wynk Nu’s Soul Cyster supplement claims to be the most complete hormone solution. Although it was developed by two sisters with PCOS, it claims to also be helpful for women with PMS, PMDD, endometriosis and menopause.

It claims that if you struggle with any of the following symptoms, this supplement is for you. 

That’s a lot of PCOS symptoms that could potentially be controlled, but can the actual supplement really deliver all of that? Let’s look at what’s inside and what the research says. 

Wynk Nu Soul Cyster Supplement Facts

Alright, let’s talk about what’s actually inside of this powder supplement. 

Magnesium Citrate 326mg

Magnesium is an essential mineral that plays a huge role in our overall health. For some reason that isn’t well understood yet, women with PCOS tend to have lower levels of magnesium too.

In terms of magnesium’s benefits for those with PCOS, it can:

• Reduce insulin resistance
• Lower inflammation
• Decrease testosterone levels
• Lessen anxiety and stress levels
• Improve sleep quality
• Improve PMS symptoms

Soul Cyster contains 326 mg of magnesium citrate. This form of magnesium is absorbed well by the body. The dose also falls right in the middle of the typical 200 to 600 mg dosage that has been used in most research studies. 

Something to be aware of though is that this particular form of magnesium can have a laxative effect for some individuals. It can cause bloating, abdominal discomfort, and diarrhea. If you struggle with constipation at baseline, this may be a good form of magnesium for you to take. But if you’re in the 20% of women with PCOS who also suffer from irritable bowel syndrome (IBS), you may want to consider a different form of magnesium, such as magnesium glycinate (1). 

Additionally, magnesium has the nice benefit of helping you relax and sleep well. Considering there’s a good amount of magnesium in the Soul Cyster powder, it may be better to take this at nighttime to take advantage of these potential benefits. 

Vitamin B6 (Pyridoxine HCl) 50mg

Vitamin B6 is a water soluble vitamin that is essential for normal immune system function and also healthy progesterone production. Since many women with PCOS don’t experience regular ovulation, progesterone levels may be inadequate. Adequate progesterone production is necessary for fertility and a healthy pregnancy.  

Some research suggests that vitamin B6 supplementation, approximately 50 to 100mg per day, may alleviate symptoms of PMS such as menstrual pain, cramping, breast tenderness, and mood swings. 

The Recommended Dietary Allowance (RDA) for vitamin B6 is 1.3mg daily for adult women; and 1.9mg and 2mg for pregnancy and breastfeeding, respectively. While the amount of vitamin B6 in Soul Cyster is significantly higher than the RDA, there don’t appear to be adverse effects of taking high amounts of this water soluble vitamin.

Zinc Gluconate 30mg

Zinc is a trace mineral that also functions as an antioxidant. Some research has found that women with PCOS are at a higher risk of having a zinc deficiency. 

In terms of common symptoms of PCOS, zinc may help: 

• Lower insulin resistance (2)
• Reduce inflammation and oxidative stress
• Decrease cholesterol levels
• Reduce symptoms of high androgen levels like hirsutism (aka excess facial hair or body hair), hair loss, and acne (3)
• Promote regular ovulation 
• Improve fertility and egg quality

Soul Cyster contains 30 mg of zinc gluconate. This form of zinc is easily absorbed by the body and a form that I do often recommend. 

The Recommended Dietary Allowance (RDA) for zinc is 8 mg for women. For pregnancy and breastfeeding, 11-12 mg of zinc is recommended. It’s difficult to get too much zinc from food sources, but it is definitely possible to get too much from zinc supplements. 

Soul Cyster contains almost 4 times the amount of zinc than the RDA for women who aren’t pregnant and breastfeeding. Taking high doses of zinc for a long period of time can cause a copper deficiency, weakened immune system, and digestive issues like nausea, vomiting, and diarrhea.

Folate (5-methyltetrahydrofolate calcium) 400 mcg DFE

Folate is also known as vitamin B9. It’s naturally occurring in a wide variety of food sources such as spinach, black eyed peas, asparagus, Brussels sprouts, and rice. 

Folate and folic acid (the synthetic version of folate) have long been known to be important for pregnancy, particularly for preventing neural tube defects like spina bifida. More recently, research has linked folate to an improvement in fertility and reproductive health. In fact, recent studies have confirmed that higher folate intake is associated with lower risk of anovulation and ovulatory infertility, shorter time to get pregnant, and greater success with infertility treatment (4).

The recommended dietary allowance (RDA) for folate for adult women is 400 mcg DFE. During pregnancy, the RDA increases to 600 mcg DFE, and 500 mcg DFE while breastfeeding. 

Soul Cyster contains 400 mcg DFE, which meets the RDA for adult women. I do also like the methylated form of folate that’s found in this supplement. 

There is some debate as to whether the synthetic form folic acid is well absorbed by those with the common MTHFR gene variation (5). As with any supplement, it’s always a good idea to talk to your healthcare provider to ensure it’s a good choice for you, especially if you’re trying to conceive. 

Selenium (L-selenomethionine) 200mcg

Selenium is an essential mineral that’s naturally found in foods like Brazil nuts, seafood, red meat, dairy, and eggs. It acts as an antioxidant in the body to lower inflammation and plays a pivotal role in thyroid function. 

As far as PCOS goes, selenium may help to:

• Improve insulin sensitivity
• Reduce inflammation
• Lower cholesterol levels
• Optimize thyroid function
• Improve egg quality 

Soul Cyster uses 200 mcg of selenium in their supplement, which is a common amount found in clinical trials as beneficial. 

The RDA (recommended dietary allowance) for selenium is 55 mcg daily for non-pregnant females. The RDA goes up to 60 mcg and 70 mcg of selenium daily for pregnant and breastfeeding women, respectively.  

It’s important to note that excess selenium intake can cause adverse health outcomes, including some symptoms that you may be trying to correct: hair loss and nail brittleness. The tolerable upper limit has been set at 400 mcg daily, which is double the amount of selenium that’s found in the Soul Cyster supplement (6). 

If you take other supplements that contain selenium, or eat a lot of high selenium foods, it may be relatively easy to overdo it on selenium. 

Chromium Picolinate 120mcg

Chromium is an essential trace mineral that’s naturally found in foods like ham, grape juice, and whole grains. 

When it comes to PCOS, chromium may help to: 

• Lower fasting glucose and insulin levels
• Reduce testosterone levels
• Decrease body weight and BMI
• Regulate menstrual cycles
• Improve ovulation and fertility rates
• Lower inflammatory markers

It’s important to note that while some research studies found positive benefits, others did not find any significant benefits for chromium supplements. In fact, a 2018 systematic review found that chromium supplementation had little benefits on weight loss, glucose control, and hormonal disturbances in women with PCOS. Another 2018 meta-analysis also found that chromium didn’t have a significant impact or benefit for those with PCOS. 

Most research studies that did find a positive benefit used a dose of 200 to 1000 mcg chromium daily. Soul Cyster contains 120 mcg chromium picolinate, which may not provide a lot of benefits at this dose. 

Vitamin D3 50mcg

For women with PCOS, vitamin D deficiency is particularly common. In fact, 67-85% of women with PCOS are vitamin D deficient according to one study. 

Considering vitamin D is actually a hormone, it makes sense that many people with PCOS are deficient in this vitamin, which can contribute to the hormone imbalances that are seen with PCOS.

Research has shown that having optimal levels of vitamin D can: 

• Improve menstrual cycle regulation
• Increase ovulation rates and the amount of mature follicles
• Decrease glucose and insulin levels
• Lower inflammation
• Decrease testosterone levels

Soul Cyster contains 50mcg, or 2000 IU (international units) of vitamin D3, which is a well-absorbed form of vitamin D. This may be enough vitamin D supplementation for you. Although, it may not be optimal for everyone’s needs though, especially if you’re deficient. 

Some common vitamin D doses I’ve seen recommended by research studies and medical doctors for those with PCOS range from 2,000 IU daily to 50,000 IU once per week. Your doctor can screen you for vitamin D deficiency with a simple blood test and advise you on supplementation if necessary. 

Myo-Inositol 2000mg & D-Chiro Inositol 50mg

You may have heard of this one before since inositol is the most well-studied supplement for PCOS. Honestly, it has some pretty impressive results too. The Soul Cyster blend of myo-inositol and d-chiro inositol has the same 40:1 ratio that I typically recommend if you’re going to try inositol. Read more about my favorite inositol supplement here: 12 Ovasitol Benefits for PCOS & Hormone Health.

Inositol can help: 

• Improve insulin sensitivity
• Decrease body weight and BMI
• Reduce inflammation  
• Lower high cholesterol levels
• Reduce carbohydrate cravings
• Lower testosterone levels, which can be contributing to hirsutism and hair loss 
• Restore ovulation and promote regular menstrual cycles 
• Increase fertility by improving egg quality, pregnancy rates, and IVF outcomes
• Decrease the risk of gestational diabetes in pregnancy 
• Improve thyroid function in hypothyroidism

Myo-inositol alone can have positive effects on PCOS symptoms too. However, research seems to favor the myo-inositol plus d-chiro inositol blend, especially if weight loss is one of your goals (7).

The recommended dosage of inositol is 2,000 to 4,000 mg myo-inositol plus 50 to 100 mg d-chiro inositol daily, so the amount used in this supplement falls within the lower end of the recommended range. 

If you’ve ever taken Ovasitol before, Soul Cyster is the same ratio of inositols that is found in there. If you followed the instructions for Ovasitol and were taking two scoops per day (or two packets per day), you were taking 4,000mg myo-inositol and 100mg d-chiro inositol daily, which is double the amount in Soul Cyster.

NAC 300mg

N-acetylcysteine (NAC) is a powerful antioxidant and amino acid found in foods. High protein foods like poultry, beef, cheese, yogurt, and eggs tend to have the highest concentrations of NAC. 

When it comes to PCOS symptoms, NAC can help:

• Reduce body weight and BMI
• Lower fasting glucose and insulin levels
• Decrease inflammation
• Reduce testosterone levels
• Lower cholesterol levels
• Increase pregnancy and ovulation rates

There have even been studies that compare NAC to Metformin in those with PCOS. In fact, in one study, NAC actually performed better than Metformin for lowering glucose, insulin, and cholesterol levels (8). It’s important to note though that this study used a dose of 1800 mg NAC daily, which is a much higher dose than what’s found in Soul Cyster.

Soul Cyster contains 300 mg of NAC per serving. The recommended dosage of NAC is 1,600 to 3,000 mg daily. The NAC dosage in Soul Cyster is significantly lower than the recommended dosage range, which may make it ineffective. 

DIM 200 mg

Diindolymethane, aka DIM, is a compound that your body naturally makes when you eat cruciferous vegetables like kale, brussels sprouts, broccoli, and cauliflower. It’s also available in supplement form.

Despite limited research, DIM has gained popularity as a potential treatment option for acne, estrogen imbalances, certain cancers, and menopausal symptoms. 

DIM helps to support natural estrogen detoxification pathways. If you have irregular periods or PMS symptoms, estrogen levels may be out of balance with your progesterone levels. This can lead to a variety of symptoms like irregular periods, painful periods, cramps, breast tenderness, and migraines.

Estrogen imbalances can also promote subcutaneous fat storage and lead to weight gain. So in theory, if DIM can support estrogen detoxification, it may be able to help promote regular periods, less PMS symptoms, and even weight loss.

The human studies that have examined the benefits of DIM are lacking. More research is needed to establish whether DIM is beneficial, who can benefit from it, and which dose is appropriate. 

DIM is available as supplements in two forms. One form is a generic crystalline formulation, which is not well absorbed by the body. Another form is a microencapsulated form called BioResponse-DIM (BR-DIM), which is much better absorbed and is the form that most research studies used (9). Most human studies have used dosages of anywhere between 100 to 300 mg DIM in supplement form.

Soul Cyster contains 200 mg, which falls in the mid-range that may be beneficial according to human studies. It’s not clear whether Wynk Nu uses the BR-DIM form, which is absorbed significantly better, in their Soul Cyster supplement.  

Other Ingredients

Other ingredients in Soul Cyster include citric acid, natural and artificial flavors, malic acid, monk fruit extract, and natural colors.

Cost

The cost for the Wynk Nu Soul Cyster supplement is pricey. It will cost you $49.95 USD for a 30 day supply. 

When purchasing, you are also signing up for automatic delivery every 30 days. This can be canceled at any time…you just need to remember to do so!

Additionally, the company appears to offer a generous refund policy. You’re able to return the supplement if you decide within 30 days of your first purchase that you don’t like it. 

Pros

• Third Party Tested. The supplement industry is not regulated like the food industry is. The Food and Drug Administration (FDA) does not regulate or approve of any dietary supplements, their labeling, or health claims. It’s not uncommon to find supplements on the market that don’t actually have what they’re advertising inside their supplements. Thankfully, Wynk Nu supplements, including Soul Cyster, are third party tested for purity and quality. 

• Uses Good Nutrient Forms. There are several different forms of vitamins and minerals that are available to purchase in supplement form, and they’re not all created equal. Soul Cyster does utilize easily absorbed forms of vitamins and minerals in their supplement.

• Convenient. Each serving is already conveniently packaged in a single-serving packet, making them easy to travel with.

• Potential One-and-Done Purchase. If your unique medical needs require you to need all of the nutrients in this supplement, this could be a great choice for you. It could prevent you from needing to purchase several different supplements, if you can benefit from all of the ingredients in this supplement.

Cons

• Possibly Unnecessary. While this can seem like appealing ways to improve your hormone health, it likely isn’t necessary. This supplement kind of seems like they took every single nutrient that has a little bit of positive PCOS research and concocted it into a supplement. That sounds awesome in theory; but in reality, it’s usually not necessary to actually see PCOS symptom improvement. 

• Taste. Although I have not tried them personally, if you are someone who is sensitive to certain flavors, this may not be for you. Many people complain about the taste of this supplement, some citing that it’s incredibly sweet.

• Possibly Inappropriate Dosage. While many of the nutrients have therapeutic dosages, some may be too high or too little to have a good effect on your health. For example, there is a high amount of both zinc and selenium in this supplement, which can sometimes contribute to hair loss if taken in excess. As always, consult with your healthcare provider to determine if this is an appropriate supplement for you before taking it. 

• Shipping Times & Practices. People complain about shipping time and the need to contact customer support for tracking info on their purchases.

• Cost. The cost may be inhibitory for some people. At just about $50 USD per month, these are not cheap. However, if you do genuinely need, and will benefit from, all of the ingredients in this supplement, it may actually be pretty cost effective for you. 

Wynk Soul Cyster Review: Is It Worth It?

Maybe. Maybe not. Unfortunately, I don’t have a straight answer for you. The answer is going to entirely depend on you and your unique needs. PCOS is a unique and complex endocrine disorder that presents differently in different people. 

Whether or not this is the best supplement choice for you will depend on: 

• Symptoms you’re struggling with
• What your root cause is
• Your goals for the future (example: are you thinking about fertility and pregnancy in the near future? If so, there likely will be better options for you.)
• Your diet (don’t miss this one: A Dietitian’s 7 Day PCOS Diet Plan PDF)
• What your lab values are or if you have any vitamin deficiencies (if you’re struggling with hair loss and it’s being caused by a severe vitamin D deficiency or an iron deficiency, this supplement isn’t going to help)

If you have determined that these nutrients are right for you, this product may be a good option since it does seem to have high quality ingredients and nutrient forms. Soul Cyster also undergoes third party testing to ensure quality and purity, which is always a good thing in my book. 

Other PCOS Supplement Reviews You’ll Love:

Ovasitol Benefits for PCOS

Best Multivitamin For PCOS: A Dietitian’s Top Brands

Happy Hormones PCOS Multivitamin Review

Is S’Moo For You? A Dietitian’s Review

A Dietitian’s Review: Flo Ovarian Support